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Na+/H+ Exchanger (NHE)

Na+/H+ exchanger (sodium/hydrogen exchanger, NHE) family exchanges Na+ for H+ according to their concentration gradients, thus promotes the regulation of the stability of cytoplasmic pH and cell volume.

There are nine isoforms of NHE in humans, some NHEs function primarily on the plasma membrane, and others are present on intracellular organelles. NHE1 is expressed in the plasma membrane of virtually all tissues and plays an important role in cardiac health. NHE2 is expressed in the gastrointestinal (GI) tract and contributes to the maintenance of stomach pH and homeostasis, whereas NHE3 predominates in the GI tract and kidneys. NHE4 and NHE5 are abundant in the stomach and brain, respectively. NHE6-9 are expressed in the intracellular compartments of many organ system membranes, but of these NHE8 is the exception and expressed apically.

1204329-34-9
4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide
CAS No: 1204329-34-9
MW: 392.8038
Purity: 95%
Pricing and Availability
1234365-97-9
17-[[[3-[(4S)-6,8-Dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-12,15-dioxa-2,7,9-triazaheptadecanamide dihydrochloride
CAS No: 1234365-97-9
MW: 1217.9705
Purity: ≥98%
Pricing and Availability
1234423-95-0
TENAPANOR
CAS No: 1234423-95-0
MW: 1145.0486
Purity: 95%
Pricing and Availability
1422252-46-7
BIXNHE1Inhibitor
CAS No: 1422252-46-7
MW: 392.8038
Purity: 95%
Pricing and Availability
159138-80-4
Benzamide, N-(aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-
CAS No: 159138-80-4
MW: 283.3467
Purity: 97%
Pricing and Availability
187870-78-6
Rimeporide
CAS No: 187870-78-6
MW: 333.3839
Purity: 95%
Pricing and Availability
187870-95-7
Rimeporide hydrochloride
CAS No: 187870-95-7
MW: 369.8448
Purity: 95%
Pricing and Availability
211813-86-4
Eniporide hydrochloride
CAS No: 211813-86-4
MW: 356.8278
Purity: 98%
Pricing and Availability
2235-97-4
5-(N,N-dimethyl)-Amiloride(hydrochloride)
CAS No: 2235-97-4
MW: 294.1411
Purity: ≥98%
Pricing and Availability
22373-78-0
Monensin sodium salt
CAS No: 22373-78-0
MW: 670.8709
Purity: 95%
Pricing and Availability