Login
Gap Junction Protein

Gap junction (GJ) channels span the plasma membranes of adjacent cells and are formed by the docking of two hemichannels (connexons) oligomerized from connexin (Cx) proteins, which consist of 21 distinct isoforms. GJs provide a direct pathway for cell-to-cell electrical signaling and metabolic communication, allowing the passage of small ions, amino acids, metabolites, tetraethylammonium and signaling molecules such as cAMP, IP3, siRNA and small peptide.

Gap junction channels provide the basis for intercellular communication in the cardiovascular system for maintenance of the normal cardiac rhythm, regulation of vascular tone and endothelial function as well as metabolic interchange between the cells. In the heart, GJs mediate electrical coupling between cardiac myocytes, forming the cell-to-cell pathways for orderly spread of the wave of electrical excitation responsible for synchronous contraction. Gap junctions also play an important role in the control of bladder contractile response and in the regulation of various immune inflammatory processes.

1507930-54-2
TAT-Gap19
CAS No: 1507930-54-2
MW: 2703.2492
Purity: 99%
Pricing and Availability
1507930-57-5
Gap19
CAS No: 1507930-57-5
MW: 1161.4367
Purity: 99.67%
Pricing and Availability
175013-84-0
Benzamide, N-[(3S,4S)-6-acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3-chloro-4-fluoro-
CAS No: 175013-84-0
MW: 391.8206
Purity: ≥95%
Pricing and Availability
197250-15-0
GAP 26
CAS No: 197250-15-0
MW: 1550.7795
Purity: 98%
Pricing and Availability
198284-64-9
GAP 27
CAS No: 198284-64-9
MW: 1304.5342
Purity: 95%
Pricing and Availability
6385-02-0
MECLOFENAMATE SODIUM
CAS No: 6385-02-0
MW: 319.1384
Purity: 99%
Pricing and Availability
916977-43-0
L-Threonine,L-valyl-L-a-aspartyl-L-cysteinyl-L-phenylalanyl-L-leucyl-L-seryl-L-arginyl-L-prolyl-L-threonyl-L-a-glutamyl-L-lysyl-
CAS No: 916977-43-0
MW: 1395.5803
Purity:
Pricing and Availability
943133-81-1
GAP-134(Hydrochloride)
CAS No: 943133-81-1
MW: 327.7634
Purity: 99%
Pricing and Availability
943134-39-2
(2S,4R)-1-(2-Aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid
CAS No: 943134-39-2
MW: 291.3025
Purity: 95%
Pricing and Availability