Login

KY 02111

KY 02111 promotes the differentiation of human pluripotent stem cells to cardiomyocytes by inhibiting Wnt signaling.<sup class="referenceList">[1]</sup> Treatment with 10 μM of KY 02111 has been shown to increase the ratio of beating cardiac colonies by 70–94% in cell aggregates of the embryonic stem cell lines KhES-1 and KhES-3 as well as the induced pluripotent stem cell lines 253G1, IMR90-1, IMR90-4, and RCHIPC0003.<sup class="referenceList">[1]</sup>
1118807-13-8
Item No.
TX008UMW
CAS No.
1118807-13-8
Molecular Formula
C18H17ClN2O3S
Molecular Weight
376.85717999999997
Pricing ＆ Availability
Pack Size Purity Price(USD) Availability Quantity
1mg 99% $10.00 in stock
5mg 99% $13.00 in stock
10mg 99% $17.00 in stock
50mg 98% $70.00 in stock
200mg 95% $239.00 in stock
WARNING This product is for research use only. SDS
Technical Information
Item No.:
TX008UMW
Product Name:
KY 02111
Description:
Synonyms:
KY 02111; KY02111
CAS Number:
1118807-13-8
MDL:
MFCD08483062
Molecular Formula:
C18H17ClN2O3S
Molecular Weight:
376.85717999999997
SMILES:
ClC1=CC=C2C(SC(NC(CCC3=CC=C(OC)C(OC)=C3)=O)=N2)=C1
λmax:
204, 223, 281, 304 nm
Solubility:
DMSO: 10 mg/ml
Shipping Condition:
Room temperature in continental US; may vary elsewhere.
References & Citations:
[1]. 1.Minami, I., Yamada, K., Otsuji, T.G., et al. A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions Cell Rep. 2(5),1448-1460 (2012).