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Progesterone Receptor

Progesterone receptor (PR) is a member of the steroid/thyroid hormone-retinoid receptor superfamily of ligand-activated nuclear transcription factors. Progesterone receptor plays a vital role in female reproductive tissue development, differentiation, and maintenance.

Progesterone receptor is able to bind to a large number and variety of ligands that elicit a broad range of transcriptional responses ranging from full agonism to full antagonism and numerous mixed profiles inbetween. Progesterone receptor, such as progesterone, induces conformation changes in PR ligand binding domain (LBD), thus mediates subsequent gene regulation cascades.

In humans, the biological response to progesterone is mediated by two distinct forms of the progesterone receptor (human PR-A and PR-B).

1023650-66-9
PF-03882845(PF03882845)
CAS No: 1023650-66-9
MW: 419.9034
Purity: 99%
Pricing and Availability
113-38-2
Estra-1,3,5(10)-triene-3,17-diol(17b)-, 3,17-dipropanoate
CAS No: 113-38-2
MW: 384.5085
Purity: 98% (HPLC)
Pricing and Availability
1253-28-7
19-Norpregn-4-ene-3,20-dione,17-[(1-oxohexyl)oxy]-
CAS No: 1253-28-7
MW: 414.5775
Purity: 95%
Pricing and Availability
126784-99-4
(11β)-17-(Acetyloxy)-11-[4-(dimethylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione
CAS No: 126784-99-4
MW: 475.6191
Purity: ≥98%
Pricing and Availability
1356154-92-1
17α-Hydroxyprogesterone-13C3
CAS No: 1356154-92-1
MW: 333.4391
Purity: 98%
Pricing and Availability
152-62-5
Dydrogesterone
CAS No: 152-62-5
MW: 312.4458
Purity: 95%
Pricing and Availability
159811-51-5
19-Norpregna-4,9-diene-3,20-dione, 11-[4-(dimethylamino)phenyl]-17-hydroxy-, (11β)-
CAS No: 159811-51-5
MW: 433.5824
Purity: 95%
Pricing and Availability
199396-76-4
Benzaldehyde, 4-[(11β,17β)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4,9-dien-11-yl]-, 1-oxime, [C(E)]-
CAS No: 199396-76-4
MW: 449.5818
Purity: ≥95%
Pricing and Availability
2919-66-6
17a-Acetoxy-6-methyl-16-methylene-4,6-pregnadiene-3,20-dione
CAS No: 2919-66-6
MW: 396.5192
Purity: 95%
Pricing and Availability
297-76-7
19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3b,17a)-
CAS No: 297-76-7
MW: 384.5085
Purity: 95%
Pricing and Availability