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quinolin-8-ol

8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice[1][2][3][4][5].
148-24-3
Item No.
TX001GIM
CAS No.
148-24-3
Molecular Formula
C9H7NO
Molecular Weight
145.158
Pricing ＆ Availability
Pack Size Purity Price(USD) Availability Quantity
100g 98% $6.00 in stock
500g 98% $23.00 in stock
1000g 98% $38.00 in stock
WARNING This product is for research use only. SDS
Technical Information
Item No.:
TX001GIM
Product Name:
quinolin-8-ol
Description:
Synonyms:
8-Hydroxyquinoline
CAS Number:
148-24-3
MDL:
MFCD00006807
Molecular Formula:
C9H7NO
Molecular Weight:
145.158
SMILES:
OC1=CC=CC2=C1N=CC=C2
Shipping Condition:
Room temperature in continental US; may vary elsewhere.
References & Citations:
[1]. Lawung R, et.al. Repositioning of 8-hydroxyquinoline derivatives as a new promising candidate for combating multidrug resistant Neisseria gonorrhoeae. EXCLI J. 2018 Aug 23;17:840-846. .
[2]. 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells. J Biol Inorg Chem. 2010 Feb;15(2):259-69. .
[3]. Zhai S, et.al. Tumor cellular proteasome inhibition and growth suppression by .
[4]. Hamoud MA, et.al. Effects of quinoline and 8-hydroxyquinoline on mouse bone marrow erythrocytes as measured by the micronucleus assay. Teratog Carcinog Mutagen. 1989;9(2):111-8. .
[5]. Searle CE. The selective depigmenting action of 8-hydroxyquinoline on hair growth in the mouse. Br J Dermatol. 1972 May;86(5):472-80.  .